TVT - 2005-2012
Is there a plumber in the house? The TVT study sought to compare the safety and efficacy of tube shunt surgery to trabeculectomy with mitomycin C (MMC) in eyes with prior intraocular surgery. Patients aged 18-85 years old with intraocular pressure (IOP) ≥ 18 mm Hg and ≤ 40 mm Hg on maximum tolerated medical therapy, and who had previously undergone cataract surgery and/or failed filtering glaucoma surgery were randomized into 2 groups: the 350 mm Baerveldt implant group (n = 107) and the trabeculectomy with MMC group (n = 105).
TVT is a landmark study in changing practice patterns to expand tube implantation in cases beyond refractory glaucoma. This study demonstrated that tube implantation is more efficacious in lowering IOP in patients who failed previously filtration surgery, rather than undergoing a repeat trabeculectomy.
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