Take your vitamins every day, free of advanced AMD you’ll stay. The Age-Related Eye Diseases Study (AREDS) was designed to study the clinical course of age-related macular degeneration (AMD) and age-related cataract. It included two double-masked, placebo-controlled, randomized clinical trials to test the effect of a vitamin formulation (500 mg vitamin C, 400 IU vitamin E, 15 mg β-carotene, with or without 80 mg zinc and 2mg copper) on the progression of these two conditions. AREDS enrolled 4,757 people aged 55-80 years to the long-term multicenter study, following them for an average of 6.3 years.
AREDS was a landmark study because it confirmed the effectiveness of this popular antioxidant formulation in decreasing the progression of severe AMD in the high-risk elderly population. It also left more to follow with AREDS2.
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